France's leading nutritionist Dr. Jean-Michel Cohen pinpoints why you struglle with other weight-loss diets and shows how to achieve your ideal weight while embracing life's pleasures.

The Parisian Diet is a progressive weight-loss plan that keeps you motivated through the Café, Bistro, and Gourmet phases until you reach your ideal weight. Strongly opposed to "extreme" diets and the inevitable weight gain that ensues, Dr. Cohen proposes a sensible
and holistic approach that addresses the physical, psychological, and cultural factors that impact our ability to control our relationship with food. His method encourages a global change in attitude towards what we eat. Based on habits and food choices typical of the Parisian lifestyle, the simple, delicious, and satisfying menus emphasize the use of fresh
ingredients and a balanced intake throughout the day. The Parisian Diet is not a fl ashin- the pan fad, it's a new approach to food and a way to celebrate life, helping you look and feel your best. Read more Close

Finally the Europhysics News columns, Physics in Daily Life, are brought together in one inspiring volume. These pages hold the wonders of a candle flame, the secret of surviving the sauna heat, and the mysteries of bubbles and balloons. Find answers to questions like Why is water blue? How do we localize sound? Why is ice so slippery? and What is the speed of falling raindrops?
For everybody with a bit of physics background this book playfully reveals insights into everyday conundrums. This is science at its most accessible and satisfying.

This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory issues, which are discussed. The broad range of various technologies is covered whether addressing direct in vivo gene transfer like with AAV, Adeno or non-viral vectors or ex-vivo genetically engineered cells including induced pluripotent stem cells (iPS) with integrating vectors such as retrovirus, lentivirus or transposon-derived systems. The critical path to clinical implementation is covered in the second part describing currently available tools - such as molecular imaging, ex-vivo organ cultures and high-throughput technologies used for evaluation of criteria towards a go-or-no go decision to move to the clinic; in addition, utmost salient biosafety and immunotoxicology aspects are discussed.
This book is ideal for postgraduates, undergraduates, scientists, clinicians, regulators and patients' advocacy groups looking for states-of-the-art information as well as emerging prospects - including gene targeting and homologous recombination - in gene transfer intended for clinical translation.
Dr Odile Cohen-Haguenauer is the Coordinator of Clingene-NoE, the European Network for the Advancement of Clinical Gene Transfer and Therapy. Read more Close

Nuclear medicine is a specialized medical field based on the application of radiopharmaceuticals, i.e. drugs associated to radioactivity, for diagnosis or therapeutic purposes. In the past fifty years, nuclear medicine has progressed in such a way that it is now a major tool in hospitals. Nowadays, this technology enables to better detect, observe and describe diseases, and also to improve treatments. Cancer therapy is the main application of this speciality. Once injected to the patient, the radiopharmaceutical drug aims selectively at the tumoral cells, including the metastases, settles there and emits radiation. Depending on the type of radiation, the drug will either help to identify the cells or to destroy them. Recent breakthroughs in this technology bring new perspectives to oncology, haematology and neurology.
At the same time, since the beginning of the 21st century nuclear medicine has also benefited from a double revolution in terms of imaging technology. On the one hand, the Positron Emission Tomography (PET) made a real impact with a polyvalent imaging drug called FDG. On the other hand, a new tool combining functional and morphological imaging (PET-CT) was very recently made available to the medical community. This scientific book aims to introduce nuclear medicine to a larger audience, pointing out, among other things, the difficulties both physicians and patients meet when trying to access new technologies. There are still some issues to overcome, but recent scientific breakthroughs bring great hopes for patients in the near future. Read more Close

The present book is the result of diverse courses on diffusion. It is intended to give as complete an overview as possible of diffusion in solid media, while relating the process of diffusion to both their physical bases and their applications. A series of a real situations is covered in this account, from self-diffusion of radiotracers to the more complex cases of mass flow under chemical or thermal gradients or under electric fields, or diffusion in structures of lower dimensionality (surfaces and interfaces).
In all these analyses, no category of materials was favored; metals, ionic crystals, oxydes, and semiconductors all had their turn. Only polymers were not specifically touched. One chapter is specifically devoted to techniques for studying diffusion, including methods of numerical simulation, and a last and long chapter gives a number of metallurgical phenomena in which diffusion plays a fundamental role. Read more Close

Organizers of the 11th IRPA International Congress have wished to take advantage of this occasion to launch a new series of books dedicaded to review the current important problems of concern in radioprotection assembling within this book contributions from the worldwide and most famous specialists in their respective fields. All aspects of radioprotection are treated, throught synthetic articles accessible to all.

Where will humanity stand at the dawn of the 22nd century? The answer depends on our determination to control the powerful transformations that accompany the beginning of the 21st: unprecedented demographic growth, ageing of populations, irrepressible migratory flows, dramatic reduction of some natural resources, disruption of millennial climatic cycles, rapid spread of new pathologies...

A number of these transformations are part of the generally complex, often inevitable evolution of our planet, not only geo-ecologically, but also in economics, politics, society... However, many of them present a challenge to development, that unique ability of human societies to improve their condition.

To cope with these evolutions and threats, the resources offered by science have never seemed so crucial, even if science alone cannot provide the answer. Nothing less than a scientific revolution is needed, a revolution that will give us more durable control of our destiny, leading to a world of greater solidarity and respect of our environment.

All, or almost all, scientific disciplines are concerned. But the life sciences are more than any other, already engaged as they are today in a process of profound change in their concepts, exploratory techniques and applications. Read more Close

Some of the more striking results obtained or anticipated on the ground or in space at radio, infrared and visible wavelengths and in X-, gamma-ray and cosmic-rays are covered. The roles of the European Southern Observatory (ESO) and the European Space Agency (ESA) are stressed, but national initiatives are also touched upon. Input into the research system in the form of financing and personnel and output as publications are evaluated. The time frame covered extends from around 1980 till about 2020. While this book centers on European developments, comparisons with what others are doing are included.
After the war Europe in science had fallen far behind the US. Thanks to European cooperation equality has again been reached. Through ESO's Very Large Telescope and ESA's missions, like the Infrared Space Observatory, X- and gamma- ray satellites, Mars Express and others, Europe is fully and independently present at the forefront. The need to integrate the scientists and engineers from the new EU countries into the overall organization of European science is noted, an integration which ultimately could extend even further eastward. This book addresses a wide audience: astronomers and space scientists, students, politicians involved in science funding, amateur astronomers and the educated public with an interest in the science and technology achievable by European cooperation. Read more Close

IPSN compiles and reviews the available information on artificial radioactivity in seas and oceans. The data collected in this book give an assessment of radionuclide distributions which will be useful to address scientific and wider public concerns about radionuclides found in the aquatic environment.

For more than a half-century, Mats Hillert has contributed greatly to the Science of Materials. He is widely known and respected as an innovator and educator, a scientist with an enormous breadth of interest and depth of insight. The difficult choice of twenty-four papers from a publication list of more than three hundred was carried out in consultation with him. He also suggested or approved names of those scientists who would be invited to write brief introductions to each of the papers.

A brief reading of the topics of the selected papers and their introductions reveals something of their range and depth. Several early selections - including internal reports of the Swedish Institute for Metal Research, published here in their original shape - contained seminal material that established Mats as a leading figure in the study of phase transformations in solids. Others established his presence in the areas of solidification and computational thermodynamics.

This volume represents a judicious sampling only of Mats Hillert's extensive body of work; it is necessarily incomplete, but it is hoped and expected that it will prove useful to students of Material Science and Engineering at all levels, and that it will inspire the further study and appreciation of his many contributions. Read more Close