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John Libbey
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Focal cortical dysplasias: new advances for curing epilepsy
Francine Chassoux, André Palmini
- John Libbey
- 9622311370019
The book marks the 50th anniversary of the first description of Taylor's focal cortical dysplasia, which revolutionized the world of epilepsy and traces the history of the evolution of concepts in the world of clinical and basic research.
A broad panel of experts in epileptology, neurophysiology, neuropathology, genetics, imaging and brain surgery who have been working on the subject for decades has put together this book, and take stock of the latest advances to better understand and treat epilepsies related to focal cortical dysplasias.
This book offers you:
Concrete information on the best use of all available tools and the most effective medical care.
The basis for possible targeted therapies developed from the latest advances in genetic and molecular research.
The + of the book
--> Dozens of illustrations : A selection of neuropathological slices, structural and functional imaging, surface and depth electroencephalographic recordings (SEEG), intraoperative views, explanatory diagrams and decision trees.
--> State-of-the-art techniques in multimodal imaging (high-field MRI, PET, SPECT, image post- processing), neurophysiology (SEEG, EEG-fMRI, MEG, EEG-HR) and neurosurgery (targeted resections in functional areas, alternative techniques) are detailed and clearly presented in a didactic approach.
--> It is written in English.prêts illimités
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LCPThe role of EEG in the diagnosis and classification of the epilepsies and the epilepsy syndromes
Michalis Koutroumanidis
- John Libbey
- 9620103600016
An updated version of the ILAE classification and the differential diagnosis of epilepsies, written by international experts in clinical epileptology and EEG.The book covers the clinical and EEG features as well as the recording protocols of all paediatric and adult epilepsy syndromes, rates diagnostic confidence according to the findings in hand and the available clinical information.The combination of the clinical EEG information, its dynamic layout and the 150 EEGs makes this book a reference guide in daily clinical practice for all electroencephalographers, epileptologists, general and child neurologists, EEG technologists and epilepsy nurses
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LCPEpilepsy and cannabinoids
Alexis Arzimanoglou, Collectif
- John Libbey
- 3664181541928
There has been growing interest in the use of cannabis-based products for the treatment of a wide range of diseases, including epilepsy. A number of studies were published during the last 5 years
demonstrating efficacy of purified CBD for the control of a large spectrum of seizure-types, particularly those observed in severe childhood epilepsies, such as Lennox- Gastaut and Dravet syndromes. This book, co-authored by leaders in the field of epileptology, critically reviews recent data from clinical trials. Authors discuss issues related to pharmacology, drug interactions, efficacy, potential adverse events and
long-term effects on development and behaviour. Child and adult neurologists and all clinicians contributing to epilepsy care will find useful information on the best practices, when using purified CBD for the treatment of
drug-resistant epilepsies.prêts illimités
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LCPEncephalopathy related to status epilepticus during slow sleep : linking epilepsy, sleep disruption and cognitive impairment
Guido Rubboli, Carlo Alberto Tassinari
- John Libbey
- 3664181532407
In the last years, clinical data, neurophysiological and imaging investigations, as well as genetic studies have renewed the interest on ESES. In addition, experimental findings from sleep research have opened fascinating perspectives on some possible pathophysiological mechanisms involved in this condition.
These issues are presented and discussed in this book by clinicians, neurophysiologists, sleep physiologists and geneticists. They all have been working on ESES with the aim to provide an updated overview of this special syndrome in the light of recent research.prêts illimités
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LCPAtlas of electroencephalography v.3 ; EEG, Neurology and critical care
Philippe Gélisse, Arielle Crespel
- John Libbey
- 3664181532339
The third volume of the series of Atlases deals with the use and usefulness of electroencephalography (EEG) in neurology.
While EEG is universally recognized as a first-order investigation method in epilepsy (see Volume 2), and as an important contributor in sleep medicine, practical neurology has tended to neglect the value of this classical and established neurophysiological tool. A rich, extensively commented and analyzed collection of EEG plates is presented here.
The reader will be compelled to remember that EEG is the easiest way to assess parameters like state of vigilance, risk of seizure activity, type and degree of functional impairment, in a very clinical and practical setting. The authors cover many aspects of neurological practices where the EEG may help in diagnosis and treatment: metabolic and other encephalopathies, infectious and inflammatory conditions, vascular disorders. It is particularly useful -and difficult- to distinguish between epileptic phenomena and EEG changes associated with metabolic abnormalities: a careful assessment of the EEG is of paramount practical importance here. Migraine is not always simple and there are many overlaps with other types of neurological diseases: the EEG may play a major part in helping the clinician in doubtful cases. Similarly, the diagnosis of dementia does certainly not rest on the EEG but many particular aspects concerning diagnostic overlaps or copathologies are aptly explored by the EEG. Lastly, even the neurosurgeon may need the EEG to monitor trauma, tumor, bleeding...
This Atlas will provide both examples and guidelines for the optimal use of the EEG in neurology.prêts illimités
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LCPAtlas of electroencephalography v.1 ; awake and sleep EEG
Philippe Gélisse, Arielle Crespel
- John Libbey
- 3664181532360
Fully updated and revised, the 3rd edition of the Atlas of Electroencephalography volume 1: Awake and Sleep EEG, activation procedures and artifacts retains the format and presentation that made the previous editions successful.
It is the most comprehensive EEG atlas on activation procedures, artifacts and normal EEG, covering the full spectrum of normal and unusual patterns observed during wakefulness and sleep, in children and adults. It will significantly help the visual analysis of EEG by neurologists and other specialists as well as technologists.
Electroencephalograms are shown in their native format, exactly as they appear in daily practice. Each plate is analyzed, in order to highlight the most significant elements to be used in diagnosis and interpretation. This 3rd edition includes a total of 180 EEG plates.
Philippe Gélisse and Arielle Crespel are neurologists running the Epilepsy Unit at the Montpellier University Hospital, in France. Both have extensive national and international experience in teaching about EEG and they have written numerous scientific publications in the field.prêts illimités
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LCPAtlas of electroencephalography v.2 ; the epilepsies, EEG and epileptic syndromes
Philippe Gélisse, Arielle Crespel
- John Libbey
- 3664181532384
Fully revised and updated, this second edition of the second volume of the Atlases of electroencephalography series includes more than 2/3 new high-quality digital figures. A new Classification approach to epileptic seizures and to the epilepsies became official in 2017. Several aspects in terms of terminology have been included in this book and most of the chapters have been rewritten.
The second volume of this series on the practical use and interpretation of EEG focuses on epilepsies in their diversity. It is richly illustrated, and each EEG plate is analyzed in order to highlight the most significant elements to be used both for the diagnosis and interpretation. The originality of this textbook lies in its patient-based approach, thereby avoiding the pitfall of a formal presentation of EEG documents without their clinical context. Hence electroencephalography is placed at the core of the diagnostic and therapeutic discussion concerning patients with epilepsy.
Given the practical orientation of this Atlas, the focus is on common forms of epilepsies; nevertheless, some less common, more intriguing forms have also been illustrated. A synthetic text summarizes the present approach to the main epilepsy categories.
This Atlas is designed for all the actors who may be involved with patients with epilepsy. Physicians who deal with EEG will find it a valuable tool to improve the education of their early years, to help them with their interpretations later on, and for teaching purposes when more experienced. But it will also prove useful for all the physicians interested in epilepsy, as well as EEG technologists intent on providing quality recordings, and other professionals. Thorough understanding of human epilepsies requires extensive knowledge of their EEG correlates.prêts illimités
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LCPPediatric epilepsy surgery
Collectif
- John Libbey
- 3664181532025
In 1997, Jean AICARDI, one of the most brilliant child neurologists of our era, commented on "How the view has changed" in the field of pediatric epilepsy surgery: "Surgery for epilepsy has now become a realistic therapeutic option for selected children and the field is likely to increase in the near future. It is now realised that procrastination, in the hope that new antiepileptic drugs will become efficacious, is not justified for some forms of epilepsy that can often be recognised from onset or after a relatively short course. It is also becoming clear that surgery is not reserved for a highly selected population of patients with normal intelligence and focal seizures, but may also help a proportion of more severe epilepsies if a realistic view of the problem and perspectives is taken by the partners".
Twenty years later, the most obvious and probably still the strongest reasons against epilepsy surgery in children are cultural and psychological. This book, written by members of the ad hoc ILAE Task Force for pediatric epilepsy surgery and experts in the field, is the result of continued collaborative working between pediatric epilepsy surgery centres over the years. Authors critically review all available data and set out the key elements of presurgical evaluation, the specific electro-clinical presentations per etiology, the range of outcomes to be monitored, and the surgical techniques used today.
What becomes obvious when reviewing all available data is that the key to optimized outcome in children with epilepsy is early appropriate recognition of possible surgical candidates and timely referral to centres with expertise.prêts illimités
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LCPProgressive myoclonus épilepsies ; state of the art
Berge a. Minassian, Pascale Striano, Giuliano Avanzini
- John Libbey
- 3664181532193
Progressive myoclonus epilepsy strikes healthy children and has a slow yet devastating impact upon their lives. Almost all forms are caused by single gene defects, the majority of which were identified during the genomic era.
Accurate clinical diagnosis is now straightforward and research into pathogenesis builds upon our understanding of causation. Future research is likely to lead to new therapeutic approaches while providing us with a better understanding of how the brain, the very essence of our being, operates, gene by gene. As we stand on the cusp of the post-genomic era, the emergence of unprecedented new tools, such as CRISPR and adeno-associated viruses, offers hope that these monogenetic diseases may one day be eliminated altogether.
This book outlines the genetic, pathogenetic, pathological, and clinical aspects of progressive myoclonus epilepsies within the context of the post-genomic era.prêts illimités
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LCPVisual impairments and neurodevelopmental disorders ; from diagnosis to rehabilitation
Elisa Fazzi, Paolo Emilio Bianchi
- John Libbey
- 3664181532094
A comprehensive review of visual impairment in children and possible solutions
The rising number of cases in visual disorders during development, over the last decade, has strongly influenced approaches to diagnosis and rehabilitation.
Moreover, the study of visual function has evolved not only within an ophthalmological, but also a neurodevelopmental framework: advances in our understanding of the maturation and plasticity of visual system functioning have further guided the progress of such approaches. As a result, the key importance of the developmental age is now widely acknowledged, from as early as the first months of life.
This book provides an overview of the diagnosis and treatment of visual disorders in relation to advances in neurodevelopmental studies. The concept of early and multimodal management is discussed, with a focus on neuro-psycho-ophthalmological issues. The need for training courses aimed at updating semiological aspects and methodological and rehabilitative strategies is established, as being of significant value to clinical practice.prêts illimités
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LCPSurgical neuropathology of focal epilepsies ; textbook and atlas
Ingmar Blümcke, Harvey b. Sarnat, Roland Coras
- John Libbey
- 3664181531936
The need for neuropathology reviews in epilepsy surgery tissues steadily increases. However, textbooks and case presentations highlighting and focusing on this specific topic are rare.
The authors of this book reviewed their professional experience in surgical and post-mortem neuropathology studies to compile a coherent summary of :
clinico-pathological findings,
current classification schemes,
useful protocols
research data
for major histopathological entities of brain lesions encountered in modern epilepsy surgery programs, which is hippocampal sclerosis, brain tumours associated with early epilepsy onset, malformations of cortical development, brain inflammation and malformative vascular lesions. They did not intend to be exhaustive but rather representative of the main lesions and pathologies encountered.
Thirty-two illustrated cases constitute the core of this book and will be very helpful in current practice.prêts illimités
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LCPSeizures and syndromes of onset in the two first years of life
Moshe/Cross/Bel
- John Libbey
- 3664181531912
Areference book on diagnosis, consequences and management on neonatal and infantile seizures
There is a very high incidence of seizures during the first two years of life. This may reflect multiple etiologies depending on the circumstances under which seizures occur. They may have a benign cause but for others they may lead to more devastating consequences.
This book provides new insights on how it is best to approach seizures and epilepsy in the first two years of life, to systematically create a blueprint upon which diagnostic and treatment decisions can be based.
Ongoing efforts are to understand:How seizures may occur in the developing brain?What are their consequences?Which biomarkers are being developed?What are the effective treatments to promptly stop ongoing seizures and alter the course of epileptic encephalopathies?
The data are highly reflecting the state of the art and also individualize for the particular milieu of the patient in taking into account both nature (i.e. genetics), and nurture (i.e. events that may interfere with normal development) and result in seizures and epilepsy.prêts illimités
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LCPCognitive and behavioural neurology in developmental age
Daria Riva, Sara Bulgheroni
- John Libbey
- 3664181531950
Cognitive and behavioural neurology is increasingly the focus of attention from the neurosciences, both in adults and children.This field combines a number of specialties to ensure that neurological conditions are approached from different standpoints. Appropriate cognitive/behavioural evaluation methods should based upon the known characteristics of neuropathology, molecular genetics and neurophysiology of the disorders.
An exhaustive review of a fast-growing discipline: cognitive and behavioural
This book provides an update on neurocognitive and behavioural deficits observed in developmental neurology:
epilepsy,
brain malformations,
tumours,
autistic spectrum disorders,
syndromic and non-syndromic intellectual disabilities,
cerebral palsy
CNS progressive disorders.
It aims to describe cognitive/behavioural phenotypes, define indications for treatment and rehabilitation, and enhance knowledge acquired from clinical studies.
The contents are addressed to child neurologists and psychiatrists, psychologists, paediaricians, behavioural and speech therapists.prêts illimités
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LCPPaediatric neurological disorders with cerebellar involvement ; diagnosis and management
Stefano D'arrigo, Daria Riva, Enza maria Valente
- John Libbey
- 3664181531554
This book provides an update on paediatric neurological disorders with cerebellar involvement.
The opening section of the volume is dedicated to the structure and function of cerebellum: the specific development of this organ, unlike other structures of the central nervous system, begins at a later stage of foetal development and lasts longer, even after birth, thus making the cerebellum particularly vulnerable to a wide range of insults, both genetic and acquired.
Of particular interest are chapters that focus on cerebellar disorders which may occur in isolation, or else as part of more complex malformations of the posterior fossa or in association with other supratentorial anomalies. Such conditions may be encountered both as part of 'static' congenital encephalopathies as well as in the frame of neurodegenerative or neurometabolic disorders.
Besides, the recent advances in neuroimaging and genetics allow to better characterize and define the genetic basis of an increasing number of such conditions.
The last part of the volume is dedicated to care and rehabilitation in cerebellar diseases: their correct diagnosis is pivotal in order to address patients to the appropriate genetic testing, plan clinical management and therapeutic strategies, and provide adequate counselling.prêts illimités
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LCPProgress in epileptic spasms and west syndrome/progrès dans les spasmes épileptiques et le syndrome
Guzzetta Franco
- John Libbey
- 3664181530519
Our knowledge on epileptic spasms and West syndrome is always in progress. Its wide variability concerning clinical semiology, EEG patterns and neurodevelopment is related to heterogeneous aetiologies and is believed to considerably influence diagnostic procedures and treatment selection. This contrasts with the general tendency to consider the pathogenic mechanism underlying infantile spasms as unique.
This book includes several contributions to a recent international workshop gathering up-to-date knowledge on electro-graphic and seizure semiology, neurodevelopment, surgical and medical treatment in West syndrome.prêts illimités
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LCPTransfusion medicine ; the french model
Collectif
- John Libbey
- 3664181531769
Founded on 1 January 2000 and placed under the authority of the Ministry of Health, the French Blood Establishment (EPS) is the sole public provider of national blood transfusion services in France. ISO 9001: 2008 certified and formed by seventeen regional establishments, the EFS manages the activities of collection, preparation, testing and distribution of labile blood products. Its role in maintaining the country's self-sufficiency in labile blood products, whilst meeting the highest quality and safety standards, makes it a major contributor to public health in France.
Three major features set French transfusion medicine apart from other international models:
in France, blood donation is underpinned by four founding principles: it is anonymous, voluntary, non-remunerated and not-for-profit. "Ethical blood donation" is the foundation of the French model;
this model is led by a single government agency, the EFS, which has a monopoly over the distribution of labile blood products to ensure constant availability across the country;
delivery is inseparable from immunohaematology (the EFS is the largest medical testing laboratory in France) and transfusion support, which is also provided by the EFS, to guide the prescriber towards the "right prescription" (the right product for the right patient).
Through the EFS, the French State is therefore responsible for self-sufficiency, health safety and the efficient management of the rare and precious commodity that is human blood. The French model is one of the few to provide both "ethical blood donation" and internationally recognized efficiency.prêts illimités
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LCPNeurobiology, diagnosis and treatment in autism - an update
Riva, Bulgheroni, Zappella
- John Libbey
- 3664181531578
This book provides an update on the progress made in the diagnosis, neurobiology and pharmacological treatment of autism and the rehabilitation of sufferers. It looks set to have an influence on professional practices and thus modernise the approach to diagnosis and treatment.
Autism is a disease caused by an extremely complex neurological development abnormality which is expressed in a spectrum of phenotypes and is characterised by changes in normal social interactions and a restricted, stereotypical and repetitive range of interests and activities. Its etiopathogenesis remains poorly understood.
It has become evident that the genes responsible interact with environmental factors but the molecular and pathogenic factors resulting in expression of these mutations are still not clear. These genes involve several regions of the brain and not only cause neurotransmitter dysfunction but also affect other processes. These themes are explored in the first part of the book. The other chapters cover early intervention, discussing the most appropriate original rehabilitation methods and the results obtained with identical or similar protocols in Italian centres. Lastly, psychopharmacological options and the very common comorbidities are discussed.prêts illimités
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LCPOutcome of childhood epilepsies
Collectif
- John Libbey
- 3664181531691
When epilepsy is diagnosed, it is important to try to control the seizures and the social consequences of the disease over several months both in childhood and later in life.
Although difficult to measure, these consequences can be assessed through a set of simple questions. First and foremost: What course of action to take? Should the focus be controlling the seizures, remission with or without anti-epileptic medication, quality of life or a combination of all of the above? Secondly, why try to predict outcomes and who will use this information? Thirdly, exactly how precise are these predictions?
Based on the conclusions of a workshop bringing together 49 international experts, the aim of this book is to take a critical look at our current knowledge of epilepsy outcomes in children and identify clinical and basic research pathways for the future.prêts illimités
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LCPEnvironmental changes et human health 2012 - zoonotic and vector-borne diseases
Armengaud/Delaunay
- John Libbey
- 3664181531615
This conference reflects the long-standing commitment of HSH Prince Albert II of Monaco, through His Foundation, and of the Institut Pasteur to understand and to mitigate the consequences of environmental changes on health. The primary objective of the conference is therefore to respond to the pressing need for a genuinely integrated vision of environmental changes and health challenges, and to promote a multidisciplinary dialogue among researchers from the biomedical and social sciences.
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LCPBrain lesion localization and developmental functions
Collectif
- John Libbey
- 3664181531493
The aim of this publication is to demonstrate the effect of the neural networks on cognitive functions and behavioural patterns during the development phase of a child.
Taking as a basis the previous publication in this series dedicated to brain lesion localization and development, this time it is by examining in particular the frontal lobe, limbic system (hippocampus and amygdala) and visuo-cognitive system that this book looks at the close links between the neural networks and the future development of visual, cognitive and functional capacities.
The section on the frontal lobe concentrates on anatomy, mirror neurons, memory, executive functions, the neuropsychology of frontal lobe epilepsy and the resolution of social problems which can occur as a result of brain damage.
The part on the limbic system looks at neuro-anatomical organisation and the core functions of the hippocampus and amygdala, problems of language, music, emotions or autism.
Finally, the section dedicated to the visuo-cognitive system summarises the visual field problems associated with focal lesions, the correlation with neuro-imagery and visual impairment in children born prematurely.prêts illimités
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LCPDravet syndrome
Charlotte Dravet, Renzo Guerrini
- John Libbey
- 3664181531059
Dravet syndrome is a rare and severe type of epilepsy. "Severe myoclonic epilepsy in infancy" was first described in 1978 by Charlotte Dravet, who observed common features: onset in the first year of life, fever sensitivity, multiple seizure types, often including myoclonic seizures, and cognitive deterioration. Subsequent descriptions contributed to delineating a newly recognised epilepsy syndrome. Renzo Guerrini contributed to the knowledge of the genetic basis and response to anti epileptic drugs of Dravet syndrome. New molecules have emerged, and studies on cognitive development have qualified the impairment. Families' associations have also contributed to a better knowledge of the syndrome.
Charlotte Dravet and Renzo Guerrini present here the state of current knowledge about this epilepsy type.
This book aims to provide more information on the syndrome to those neurologists, child neurologists, and pediatricians confronted with infants, children and adults who either have or are suspected to have Dravet syndrome. Even if significant gaps in our understanding of the syndrome remain, the authors hope this contribution may assist in the understanding of the disease and optimization of treatments.prêts illimités
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LCPProgress in epileptic disorders ; the mesial temporal lobe epilepsies
Felix Rosenow, Philippe Ryvlin, Hans o. Lüders
- John Libbey
- 3664181531219
This work, which results from the Marburg colloquium, chose to focus on one of the more common forms of partial epilepsies and for which surgery is often the treatment of choice, namely the mesial temporal lobe epilepsies.
Significant progress has been made over the last few years, particularly in understanding the borderline forms of this type of epilepsy.
The first part of this work concentrates on the concept of mesial temporal lobe epilepsy and its pathophysiology. The second part addresses the clinical characteristics, in particular the natural evolution of the illness, the different aetiologies and the diagnostic relevance of the ictal semiology. The third part concentrates on the clinical and experimental neurophysiology, while the fourth part addresses imaging techniques. Finally, the last part outlines the current situation of the different therapeutic strategies.
It is targeted at neurologists, neuropaediatricians, epileptologists, neurosurgeons and all doctors involved in the treatment of focal epilepsies.
Every year, a Bethel-Cleveland Symposia type colloquium takes place in alternation in Marburg, Cleveland or Lyon.prêts illimités
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LCPProgress in epileptic disorders ; extratemporal lobe epilepsy surgery
Mohamad z. Koubeissi, Robert Maciunas
- John Libbey
- 3664181531233
The theme of the Cleveland colloquium which took place in May 2010 was extratemporal lobe epilepsy surgery.
Patients with refractory extratemporal lobe epilepsy, particularly those in whom imaging examinations did not reveal any brain lesions, have a less positive prognosis after surgery than those with mesial temporal lobe epilepsy.
The semiology of seizures, the functional imaging techniques, neuropsychological evaluation and intracranial EEG are used to select surgical patients. Moreover, a large number of centres have experimented with new methods for identifying the epileptogenic area in these patients.
This work outlines diagnostic and prognostic tools available as well as epilepsy surgery.
Written by international experts who attended the Cleveland colloquium, it will be all the more useful to neurologists, neurosurgeons and epileptologists as no other work until now has focused on this subject.prêts illimités
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LCPProgress in epileptic disorders ; neuropsychology in the care of people with epilepsy
Christoph Helmstaedter, Bruce Hermann, Maryse Lassonde, Philippe Kahane
- John Libbey
- 3664181531356
A current update on the use of clinical neuropsychology in epilepsy and its future outlook
Clinical neurology has still not managed to clear a way in the daily practice with patients with all types of epilepsy despite significant advances in cognitive neuroscience and a large number of clinical studies on epilepsy and cognition.
How is it that there are only rarely major advances in the field of clinical neuropsychology? It has long been time for this question to be asked, and for an attempt to be made to bring about changes. This was the aim of the Progress in Epileptic Disorders workshop held in Toronto and the result of this book.prêts illimités
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